Question 1

What makes Anua's PDRN products different from other PDRN brands?

Accepted Answer

Anua combines PDRN with its signature heartleaf (houttuynia cordata) extract at a concentration of 77% or higher, creating a powerful synergy between advanced biotechnology and traditional botanical soothing ingredients. While the PDRN activates cellular regeneration through the A2A receptor pathway, heartleaf provides anti-inflammatory, antibacterial, and antioxidant support that calms reactive skin and protects against environmental stressors. The brand also adheres to strict clean beauty standards — no artificial fragrances, sulfates, parabens, or mineral oils — ensuring its PDRN formulations are among the gentlest on the market.

Question 2

Is Anua suitable for sensitive skin?

Accepted Answer

Yes, Anua is particularly well-suited for sensitive skin. The brand's clean beauty philosophy means its products avoid common irritants, and the heartleaf extract in their formulations provides natural anti-inflammatory and calming benefits that help soothe reactive skin.

Question 3

How do the Anua PDRN Serum and PDRN Cream work together?

Accepted Answer

The PDRN Serum is a lightweight treatment with a watery-gel texture that absorbs within seconds to deliver regenerative benefits at a cellular level — it should be applied first after toner to allow PDRN direct access to freshly prepped skin. The PDRN Cream acts as a richer moisturizing layer containing ceramides and emollients that seals in the serum's active ingredients, prevents transepidermal water loss, and provides sustained hydration for eight or more hours. Using both in sequence (serum first, then cream) maximizes the skin repair and hydration benefits by combining immediate PDRN delivery with long-lasting occlusive protection. Most users see optimal results after four to six weeks of consistent twice-daily use.

Attribute	Mastelli	Anua
Origin	🇮🇹 Italy	🇰🇷 South Korea
Products in Catalog	2	5
Product Categories	injectable, mesotherapy	cream, mask, mist, serum, toner
Average Rating	4.3	4.3
Price Range	$250–500 per session	$25–35, $25–30, $19–26, $25–35, $25–35 (10-pack)
Official Website	Yes	Yes

Mastelli vs Anua

Mastelli

Anua

At a Glance

Products Comparison

Mastelli (2)

Plinest Body

Plinest Fast

Anua (5)

PDRN 100 Hyaluronic Acid Booster Toner

PDRN Hyaluronic Acid Capsule 100 Serum

PDRN Hyaluronic Acid Hydrating Capsule Mist

PDRN Hyaluronic Acid 100 Moisturizing Cream

PDRN Hyaluronic Acid Capsule 100 Serum Mask

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