Question 1

What is the difference between Rejuran Healer, S, I, and HB?

Accepted Answer

Rejuran Healer is the original all-purpose skin booster (0.2% c-PDRN, standard viscosity) for overall skin rejuvenation, firmness, and elasticity — it is the most widely used variant and the best starting point for first-time patients. Rejuran S has a higher viscosity formulation that targets acne scars and textural irregularities by depositing concentrated PDRN directly into scar tissue for localized dermal repair. Rejuran I uses a thinner, lower-viscosity formulation specially designed for the delicate, ultra-thin periorbital skin to address dark circles, fine lines, and under-eye hollowing. Rejuran HB combines c-PDRN with non-crosslinked hyaluronic acid for dual-action hydration and regeneration, ideal for severely dehydrated or post-procedure skin. Your dermatologist will recommend the most appropriate variant based on your specific skin concerns and treatment goals.

Question 2

Is Rejuran the same as topical PDRN skincare products?

Accepted Answer

No, Rejuran products are fundamentally different from topical PDRN skincare. Rejuran products are clinical-grade injectable skin boosters administered by trained medical professionals (dermatologists and aesthetic physicians) in clinical settings using microinjection techniques. While topical PDRN products offer genuine benefits through surface and upper-epidermal penetration, Rejuran delivers c-PDRN directly into the papillary dermis where A2A receptors are most concentrated, achieving maximum bioavailability and significantly more dramatic results in skin thickness (measurable by ultrasound), elasticity (measurable by cutometer), and deep tissue repair. The two approaches are complementary: many patients use Rejuran injections for periodic intensive treatment and topical PDRN products for daily maintenance between clinical sessions.

Question 3

How often should Rejuran treatments be done?

Accepted Answer

A typical Rejuran treatment protocol involves an initial course of three to four sessions spaced two to four weeks apart, which allows each treatment to build on the collagen synthesis and tissue remodeling initiated by the previous session. Most patients begin noticing visible improvements in skin texture and elasticity after the second session. After completing the initial course, maintenance treatments are recommended every three to six months depending on individual skin condition, age, environmental exposure, and treatment goals — younger patients with mild concerns may need maintenance only every six months, while older patients or those in harsh environments may benefit from quarterly sessions. A board-certified dermatologist will assess your skin and provide a personalized treatment plan during your initial consultation.

Question 4

What is Beplain's approach to PDRN skincare?

Accepted Answer

Beplain incorporates PDRN into clean, minimalist formulations with short ingredient lists — typically 10 to 15 components compared to 30 or more in many competing products. The brand ensures that polydeoxyribonucleotide is the star active ingredient without interference from unnecessary fillers, fragrances, silicones, or additives, allowing the PDRN to interact directly with skin cell receptors and deliver maximum regenerative benefits. This approach also reduces the risk of ingredient interactions that can diminish PDRN efficacy in more complex formulations.

Question 5

Is Beplain truly a clean beauty brand?

Accepted Answer

Yes, Beplain is committed to clean beauty principles. The brand uses transparent ingredient lists, avoids unnecessary additives, artificial fragrances, and colorants, and focuses on including only ingredients that serve a clear functional purpose in each formulation.

Question 6

Who should consider Beplain PDRN products?

Accepted Answer

Beplain PDRN products are ideal for anyone who prefers minimalist skincare with transparent ingredients, especially those with sensitive or reactive skin who need gentle formulations. They are also great for consumers who want advanced PDRN regeneration benefits without the complexity of multi-ingredient products.

Attribute	Rejuran	Beplain
Origin	🇰🇷 South Korea	🇰🇷 South Korea
Products in Catalog	6	1
Product Categories	ampoule, body-care, cleanser, cream	cream
Average Rating	4.3	4.5
Price Range	$40–60, $30–40, $50–70, $55–70, $45–65, $40–50	$20–28
Official Website	Yes	Yes

Rejuran vs Beplain

Rejuran

Beplain

At a Glance

Products Comparison

Rejuran (6)

Body Lotion c-PDRN

Cleansing Milk c-PDRN

Nutritive Cream c-PDRN

Recover c-PDRN Lifting Ampoule

Turnover Ampoule c-PDRN

UV Protection Cream SPF 50+ PA+++

Beplain (1)

Cica PDRN Repair Cream

Frequently Asked Questions

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